The secrets of permanent blindness have finally been revealed by stem-cell research. This could lead to significant discoveries because not only can scientists develop more tailored drugs, but they could potentially use the stem-cell models to test hundreds of drugs in pre-clinical assays.
The world's most common cause of lifelong blindness, glaucoma, has been linked to certain genetic markers in research on the retina and optic nerve using stem cell models. These findings may lead to the development of novel treatments for the disease.
A series of eye diseases together referred to as glaucoma cause damage to the retinal ganglion cells, or neurons close to the inner eye that make up the optic nerve. Because the optic nerve of the eye receives light and sends it to the brain, glaucoma damage results in irreversible blindness. By 2040, the illness is expected to afflict almost 80 million individuals, yet there are very few effective treatments.
This study correlated 97 gene...
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