None of the current COVID-19 vaccine trials are designed to detect a reduction in any serious outcome such as hospitalisations, intensive care use, or deaths. Here’s why COVID-19 vaccine trials cannot tell us if the vaccines will save lives.
Vaccines are being hailed as the solution to the covid-19 pandemic, but the vaccine trials are not designed to tell us if they will save lives, reports Peter Doshi, Associate Editor at The BMJ (read full report below).
Many may assume that successful phase 3 studies mean we have a proven way of keeping people from getting very sick and dying from covid-19. And a robust way to interrupt viral transmission.
Yet the phase 3 trials are not actually set up to prove either, says Doshi.
“None of the trials currently underway are designed to detect a reduction in any serious outcome such as hospitalisations, intensive care use, or deaths. Nor are the vaccines being studied to determine whether they can interrupt transmission of the virus,” he writes.
He explains that all ongoing phase 3 trials for which details have been released are evaluating mild, not severe, disease – and they will be able to report final results once around 150 participants develop symptoms.
In Pfizer and Moderna’s trials, for example, individuals with only a cough and positive lab test would bring those trials one event closer to their completion.
Yet Doshi argues that vaccine manufacturers have done little to dispel the notion that severe covid-19 was what was being assessed.
Moderna, for example, called hospitalisations a “key secondary endpoint” in statements to the media. But Tal Zaks, Chief Medical Officer at Moderna, told The BMJ that their trial lacks adequate statistical power to assess that endpoint.
Part of the reason may be numbers, says Doshi. Because most people with symptomatic covid-19 infections experience only mild symptoms, even trials involving 30,000 or more patients would turn up relatively few cases of severe disease.
“Hospitalisations and deaths from covid-19 are simply too uncommon in the population being studied for an effective vaccine to demonstrate statistically significant differences in a trial of 30,000 people,” he adds. “The same is true regarding whether it can save lives or prevent transmission: the trials are not designed to find out.”
Zaks confirms that Moderna’s trial will not demonstrate prevention of hospitalisation because the size and duration of the trial would need to be vastly increased to collect the necessary data. “Neither of these I think are acceptable in the current public need for knowing expeditiously that a vaccine works,” he told The BMJ.
Moderna’s trial is designed to find out if the vaccine can prevent covid-19 disease, says Zaks. Like Pfizer and Johnson and Johnson, Moderna has designed its study to detect a relative risk reduction of at least 30% in participants developing lab-confirmed covid-19, consistent with FDA and international guidance.
Zaks also points to influenza vaccines, saying they protect against severe disease better than mild disease. “To Moderna, it’s the same for covid-19: if their vaccine is shown to reduce symptomatic covid-19, they will feel confident it also protects against serious outcomes,” Doshi writes.
But Doshi raises another important issue – that few or perhaps none of the current vaccine trials appear to be designed to find out whether there is a benefit in the elderly, despite their obvious vulnerability to covid-19.
If the frail elderly are not enrolled into vaccine trials in sufficient numbers to determine whether there is a reduction in cases in this population, “there can be little basis for assuming any benefit against hospitalisation or mortality,” he warns.
Doshi says that we still have time to advocate for changes to ensure the ongoing trials address the questions that most need answering.
For example, why children, immunocompromised people, and pregnant women have largely been excluded; whether the right primary endpoint has been chosen; whether safety is being adequately evaluated; and whether gaps in our understanding of how our immune system responds to covid-19 are being addressed.
“The covid-19 vaccine trials may not have been designed with our input, but it is not too late to have our say and adjust their course. With stakes this high, we need all eyes on deck,” he argues.
Meanwhile, it was revealed recently during the Texas Senate Committee hearing that COVID-19 vaccine trials in animals were stopped because they kept dying.
Read the report by Peter Doshi, Associate Editor at The BMJ below.
Heres-Why-COVID-19-Vaccine-Trials-Cannot-Tell-Us-If-Vaccines-Will-Save-LivesSupport GreatGameIndia
In my opinion, Coronavirus is another Flu form (in “Scientists speak” Flu = Coronavirus) and if left untreated, for 10 to 14 days of self isolation it becomes Covid in the head and body – which is when test vaccines are supposed to kick in and stop the Covid from occurring.
If you do my simple, free, salt water cure, which I have posted elsewhere here, but am happy to provide anytime, if requested – I fail to see why anyone, in their right mind, would want to not murder Coronavirus in the head, before it ever gets to be Covid, in the head and body, which my salt water cure does and it has kept me safe for 26.5 years, I am never ill.
If nobody had to die from Covid, if they had been allowed to use my free salt water cure, what then of the above vaccines?
It has never been about a virus but has always been about the vaccine and all of it planned long ago. This third and fourth wave of the virus was planned long ago by the puppet masters who own the central banks, including the Bank of China. These imposters are the puppet masters whose messiah is Lucifer/Satan. It is they who have created the free slave world in which we all live today. See my blog at tinyurl.com/matrixofgog to find out who they are…
OPERATION LOCKSTEP FROM THE ROCKEFELLER PLAYBOOK:
The Plandemic:
“1st Phase: Common/cold/Flu. Mild symptoms at most. Media endorsement of mass paranoia and fear. Flawed testing system utilized, which picks up any genetic material in the body and triggers a positive result. Inflation of Covid case numbers, through changing of death certificates, double-counting, and classifying all deaths including other diseases and natural causes as Covid19. Lockdown will condition us to life under Draconian laws, prevent protests and identify public resistance.
2nd Phase: The 1st Phase will lead to compromised and frail immune system through lack of food, social distancing, wearing of masks, and lack of contact with sunlight and healthy bacteria. Exposure to 5G radiation will further attack the immune system. Thus, when people re-emerge into society, more people will fall ill. This will be blamed on Covid19. This will all occur before the vaccination is ready to justify it. A longer and more potent lockdown will follow until everyone takes the vaccine.
3rd Phase: If majority of people resist the vaccine, a weaponized SARS/HIV/MERS virus will be released. A lot of people will die from this. It will be survival of the fittest. It will also be the ultimate push for everyone to be vaccinated, in order to return to normality. Those who have taken the vaccine will be at war with those who have not. It will be anarchy from all sides.”
“Covid-19means the ‘certificate of identification of vaccination with artificial intelligence’ and ’19’ was the year in which it was created.”
we dont need any trials since we are no users of MSM lies. we get our victims info
on a daily basis only in free nets so long censorship it alows .
THE HYSTERICAL PROPAGANDA OF PRESSTITUDES FOR COVID WHAT
NOT EXIST AS LONG IT IS NOT VACCINATED SOUNDS LIKE AN OLD
RUSTLING LP !
Moderna Vaccine
• 94% efective
• Number of shots: 2 shots, 28 days apart
• Approved for use in people aged 18 years and older
• Ingredients: messenger ribonucleic acid (mRNA),
lipids (SM-102,
polyethylene glycol [PEG] 2000
dimyristoyl glycerol [DMG], cholesterol, and
1,2-distearoyl-sn-glycero-3-phosphocholine [DSPC]),
tromethamine, tromethamine hydrochloride,
acetic acid, sodium acetate, and sucrose
• Explanation of ingredients:
– mRNA: Like the Pfzer BioNTech vaccine, Moderna’s also uses
mRNA technology to build antibodies against COVID-19.
– Lipids: Nanolipids help deliver the mRNA to the vaccine
recipient’s cells. Nanolipid components of the Moderna
vaccine include: (SM-102, 1,2-dimyristoyl-rac-glycero3-
methoxypolyethylene glycol-2000 [PEG2000-DMG], cholesterol,
and 1,2-distearoyl-snglycero-3-phosphocholine [DSPC])
– The remaining ingredients, including acids (acetic acid), acid
stabilizers (tromethamine and tromethamine hydrochloride),
salt (sodium acetate), and sugar (sucrose) all work together to
maintain the stability of the vaccine after it’s produced.
According to a Cayman Chemicals safety data sheet on SM-102,
published in April of 2021,
the substance is “For research use only, not for human or veterinary use.”
Product identifier
· Trade name: SM-102
· Synonym 8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester
· Article number: 33474
· Application of the substance / the mixture For research use only, not for human or veterinary use.
· Details of the supplier of the safety data sheet
· Manufacturer/Supplier:
Cayman Chemical Co.
1180 E. Ellsworth Rd.
Ann Arbor, MI 48108
USA
· Information department: Product safety department
· Emergency telephone number:
During normal opening times: +1 (734) 971-3335
US/CANADA: 800-424-9300
Outside US/CANADA: 703-741-5970
******According to a Cayman Chemicals safety data sheet on SM-102,
published in April of 2021,
the substance is “For research use only, not for human or veterinary use.”
NOTE: research in a lab NOT RESEARCH ON HUMANS WHICH GOES AGAINST THE NUREMBERG CODE!
These vaccine trials are unethical and our Governments are co-conspirators in the genocide of humanity.
Two lab rats were talking… One said: “They are going to test a COVID Vaccine on us tomorrow. Do you think that it is a good idea?”
The other lab rat answered: “Hell no! They haven’t finished testing the vaccine on humans yet!”
THERE IS NO INFORMED CONSENT !!!
Human clinical trials will not be completed until 2023!
Spike Proteins will KILL YOU !!!
THERE IS NO CURE !!!
Corporates started forcing there employees to either register for vaccines or showcase vaccination ID if already taken as they don’t want any employee to be without vaccination.
Any employee without vaccination is vulnerable and a danger to other employees. Hence it’s there unofficial policy that evey employee SHOULD Be Vaccinated !!!
Forced vaccination has already started in india corporates.
Ultimately, all of the blurb here and there, comes down to one thing, for, or against, test vaccines and in America, will you refuse test vaccines when the National Guard, or Government people who are knocking on house doors, one after the other, call to give each of you, your free test vaccines?
You have 2 choices, at this point in time, both of them free
1) Test vaccines
2) My free, salt water cure, which I have been doing to myself for the past 26.5 years, I am never ill and I am wearing surprisingly well for my age (74). Look much younger than my years, so I am frequently told.
At least, I have given you a choice, where one did not exist before.
I will never submit to any experimental test vaccines, but I’m up for the short haul anyway, another 10 years or so and I will be discovering if there is really life after death, or not (much laughter) I don’t give a sh*t.
You had better make up your mind while you have a choice, because we are all under the same hammer, sooner or later.
Yes or No!! and it has to be a gut reaction, then and there, because if you dither, you are gone and you will get the test vaccines – no guts, no glory – and there is only one person who can make that decision for you – You!!
Richard
Can you please explain me how the salt water cure works? Thank you!
@Nishaa: how can unvaccinated endanger the vaccinated? The vaccinated should be protected, right? Otherwise what is the use of vaccination in the first place?? 🤦♀️
The absolute efficacy percentages of the Pfizer vaccine is 0,7% and Moderna: 1,1%!!!
The 95% are relative risk reduction.
At first I didn’t care about the relative and absolute risk reduction until I understood his explanation… Nobody cares about the relative risk reduction. Everyone wants to know the risk reduction compared to if you didn’t have had the injection. This percentage is what you want to know to decide wether you should vaccinate yourself or not.
What dr. Ron Brown explains it very simple. There are two types of effectiveness: absolute and relative effectiveness. At first I thought what the heck. As long as it is effective, then remedy is good. Now that I understand it better, there is a world of difference.
The FDA requires for studies for use in humans to publish the absolute risk reduction number in addition to the relative risk reduction. It is important to know how much you will do better if you do take the drug compared to the control group that does not get it.
Suppose in the group that has been vaccinated, one in a hundred will get an infection. So 1% will get an infection.
In the control group, two in a hundred get an infection. So in this group 2% will get an infection.
Absolute risk reduction: 2% -1% = 1%
Relative risk reduction: 1%: 2% = 50%.
If someone says to me that if I vaccinate I have 1% less chance of an infection, then I think: well for that one percent, I will not take an experimental new vaccine that was never allowed to be used on humans before, because all laboratory animals previously had the bobbed. Now they have skipped the animal trials.
At 50%, however, it sounds a lot better. He has calculated that the relative absolute risk reduction.
After the data from the studies were released, he calculated the absolute risk for Pfizer and Moderna vaccines:
0.7% Pfizer absolute risk reduction
1.1% Moderna absolute risk reduction
For some people, a 1% chance of reducing an infection than the unvaccinated is already important enough to be injected. I am for freedom, happiness. Everyone should certainly be able to choose for themselves. However, pharmaceutical companies must adhere to the guidelines and publish these figures. If people are well and honestly informed, they are better able to make an informed decision.
Now that they deliberately withhold information, this only increases people’s suspicion.
And that there are no medicines is not correct. The major Pharmaceutical companies are subsidizing studies to cast negative light on the effectiveness of Hydroxychloroquine, Ivermectin, Budesonide, etc.
In many countries, doctors use Ivermectin with great success. India was an example of this. It wasn’t until they stopped taking ivermectin and vaccinated people that the rates of infections skyrocketed.
The reason why they invest a lot of money in sabotaging the studies (just like at the time with hydroxychloroquine, of which it is now admitted that it works), is that otherwise they are immediately obliged to stop the human trials. After all, if an alternative medicine is available, no one around the world may be vaccinated immediately. After all, new, experimental technology must have been tested on humans for at least five years before it can be administered to the masses. And the big pharmaceutical companies want to do everything they can to obtain the FDA Approval by 2023 that they do not have now. Then they can then administer four injections per person per year (after all, at least two mutations per year).
https://youtu.be/Jkwn5I8tLmE
Steven Fishman – I enjoyed your lab rat joke. Lab rats are less gullible than humans it seems!
Even after vaccination one can still get infected.
Unvaccinated person carries a risk as infection chances are high as per there logic.
Hence cabal is trying to get digital covid passport for everyone.
But now as per data it’s other way around.
Vaccinated person is becoming a carrier.
Where there is high number of vaccination there is high number of cases.
Nishaaa, that is because of Frequency Transmissibility Shedding by “Vaccinated” persons. The spike proteins cause MITOCHONDRIAL CANCER, because the 50 BILLION SPIKE PROTEINS replicate and deprive mitochondria of oxygen, killing your lungs, heart and brain. Please recognize that these spike proteins are MICROSCOPIC and are transmitted in the air through the breath, belching, and farting [pardon my crudeness] of the “Vaccinated” anywhere in proximity to the Unvaccinated. “Vaccinated” people ARE the carriers of this instrument of death. Since it is unlikely that THEY will be isolated from US, then we are conclusively all of risk of being infected.
I also forgot to mention that the world’s blood supply is now tainted with toxic Messenger RNA Spike Proteins. Not a good idea to get surgery until the blood supply [if ever] is analyzed and segregated,
In the US year 2020 345.000 died of COVID that 0.107% The COVID FRAUD is what it is GREATREJECT.ORG