All You Need To Know About Merck’s Covid Pill Molnupiravir

Molnupiravir was developed for the treatment of Influenza. According to whistleblower complaint Molnupiravir has mutagenic properties and may change your DNA. Now, Molnupiravir has been repurposed for COVID-19. Merck has entered into agreements with Indian manufacturers and has also announced $5 million of donations to enter into Indian market. Here is all you need to know about Merck’s Covid pill Molnupiravir.


Merck covid pill molnupiravir

Molnupiravir was developed for Influenza

Molnupiravir (development codes MK-4482 and EIDD-2801) is an experimental antiviral drug which is orally active and was developed for the treatment of influenza.

It is a prodrug of the synthetic nucleoside derivative N4-hydroxycytidine, and exerts its antiviral action through introduction of copying errors during viral RNA replication.

The drug was developed at Emory University by the university’s drug innovation company, Drug Innovation Ventures at Emory (DRIVE).

It was then acquired by Miami-based company Ridgeback Biotherapeutics, who later partnered with Merck & Co. to develop the drug further.

Molnupiravir may change your DNA

In April 2020, Rick Bright, who was removed as head of the Biomedical Advanced Research and Development Authority (BARDA) before the approval of the drug, submitted a whistleblower complaint asserting that Ridgeback pressured BARDA to provide funding to manufacture EIDD-2801 despite Bright’s concerns that similar drugs in its class have mutagenic properties.

A previous company, Pharmasset, that had investigated the Molnupiravir’s active ingredient had abandoned it over similar concerns.

In genetics, a mutagen is a physical or chemical agent that permanently changes genetic material, usually DNA, in an organism and thus increases the frequency of mutations above the natural background level.

As many mutations can cause cancer, such mutagens are therefore carcinogens, although not all necessarily are. All mutagens have characteristic mutational signatures with some chemicals becoming mutagenic through cellular processes.

These claims were denied by George Painter, CEO of DRIVE, noting that toxicity studies on Molnupiravir had been carried out and data provided to regulators in the US and UK, who permitted safety studies in humans to move forward in the spring of 2020.

At that time, DRIVE and Ridgeback Biotherapeutics stated they planned future safety studies in animals.

Merck’s Covid Pill Molnupiravir

In late July 2020 Merck, which had been partnering with Ridgeback Biotherapeutics on developing the drug, announced its intention to move Molnupiravir to late stage trials beginning in September 2020.

On October 19, 2020, Merck began a one year Stage 2/3 trial that focused on hospitalized patients.

In June 2021, the U.S. Department of Health and Human Services committed to buy US$1.2 billion worth of molnupiravir (approximately 1.7 million courses) from Merck if it received an emergency use authorization (EUA) or approval from the U.S. Food and Drug Administration (FDA).

On 1 October 2021, Merck stated that an independent advisory board that had been monitoring the COVID-19 clinical trial recommended that recruitment into the study be stopped early because of convincing evidence of the drug’s benefits, reducing the risk of hospitalization or death by 48%.

Merck announced plans to seek an EUA from the FDA, and to submit marketing applications to other global drug regulators. The company announced plans to license the drug to generic manufacturers, to accelerate its availability.

Merck’s Molnupiravir agreements with India

Merck has announced that the company has entered into non-exclusive voluntary licensing agreements for Molnupiravir with five established Indian generics manufacturers.

Merck has entered into these agreements to accelerate availability of molnupiravir in India and in other low- and middle-income countries (LMICs) following approvals or emergency authorization by local regulatory agencies.

“The scale of human suffering in India at this moment is devastating, and it is clear that more must be done to help alleviate it. These agreements, toward which we have been working as we have been studying molnupiravir, will help to accelerate access to molnupiravir in India and around the world,” said Kenneth C. Frazier, chairman and CEO, Merck.

“We remain committed to aiding in the global response that will bring relief to the people of India and, ultimately, bring an end to the pandemic.”

The agreements have been signed with Cipla Limited, Dr. Reddy’s Laboratories Limited, Emcure Pharmaceuticals Limited, Hetero Labs Limited and Sun Pharmaceutical Industries Limited – five generics manufacturers with World Health Organization (WHO) Pre-Qualified Manufacturing facilities and experience as major suppliers to global and key LMIC procurers.

Under the agreements, Merck will provide licenses to these manufacturers to supply molnupiravir to India and more than 100 LMICs. Merck is also in discussions with the Medicines Patent Pool to explore the potential for additional licenses.

Separately, Merck will also donate more than $5 million worth of oxygen-production equipment, masks, hand sanitizer and financial aid to support relief efforts in India.

Molnupiravir sold at 40 times Cost price

According to a report, the US Department of Defense financed COVID pill Molnupiravir is being sold by Merck at 40 times the actual cost price.

A 5 day course of molnupiravir, costs $17.74 to produce, according to a report published by The Intercept issued last week by drug pricing experts at the Harvard School of Public Health and King’s College Hospital in London.

However, Merck is charging the U.S. government $712 for the same amount of medicine, or 40 times the price.

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20 Responses

  1. An mRNA pill, whatever next – do this instead:
    Overburdened health authorities are trying to contain the pandemic through early interventions that protect the vulnerable regions of the human respiratory tract: the oral and nasal cavities. These regions are home to millions of viral particles that can be transmitted long-range through aerosolized droplets, increasing the risk of infection to caretakers and other highly exposed groups, like frontline workers. Since early 2020, there have been diverse clinical studies in repurposed antivirals, which can act as an adjunct to vaccination.
    7 conditions for onset Flu or Coronavirus: taste, fever, new persistent cough, chills, appetite loss and muscle aches.
    The Achilles Heel of Coronavirus, is while it is still in the developing stage as Coronavirus/Covid in the warm, wet areas inside the nasal passages of your head (nose) and before it gets to become Covid in your head and lungs, 10 to 14 days later. If Coronavirus is not treated with my free iodine salt clean water cure to flush out your nasal passages, as soon as possible, or during self isolation, it becomes Covid, which is where the money is. You cannot catch Covid! Always breathe through your nose and keep your mouth shut, because you really don’t want the Coronavirus to seed itself in your lungs!! My free salt water cure has “absolutely nothing” to do with mRNA test vaccines. Treating Coronavirus with my free iodine salt clean water cure, flushes out the nasal cavity and kills Coronavirus, before it gets to be Covid, irrespective of if you have had mRNA vaccines or not. Mix one heaped teaspoon of iodine salt in a mug of warm or cold clean water, cup a hand and pour some of the solution in, then sniff or snort that mugful up into your nose, spitting out everything which comes down into your mouth, by so doing, you flush out your nasal cavity, where Coronavirus lives. If you get a burning sensation (which lasts for 2-3 minutes) then you have a Coronavirus infection.When the soreness goes away, blow out your head with toilet paper and flush away, washing your hands afterwards and continue doing my salt clean water nasal cavity flush cure, morning, noon and night, or more often, if you want, until, when you do my free salt water cure, you don’t experience any soreness at all in your nasal cavity. While you are at it, swallow a couple of mouthfulls and if you get a burning sensation in your chest, then you are killing the Covid/Bronchitis there too, so keep it up, each time you do a salt water sniffle, until the soreness in your head and lungs goes away – job done. Pour some of the solution on a flat surface and allow to dry and see what you have then. This is what coats the nasal passages in your head and kills Coronavirus/Covid off. You can see why it is so effective. This is what I have done for the past 27 years and I am NEVER ill, nor do you need to be either.
    Please pass it around to everyone who wants to give it a try.
    “Even so, a key issue is that the current vaccines block severe disease but do not prevent infection, said Dr. Gregory Poland, a vaccine scientist at the Mayo Clinic. That is because the virus is still capable of replicating in the nose, even among vaccinated people, who can then transmit the disease through tiny, aerosolized droplets”
    Reuters – what my free salt water cure stops.
    He added that “Current vaccines are great at preventing [CO1] serious infection deep in the lungs, but not at blocking infection in the upper airways. What’s needed is a nasal-spray (vaccine) that would stop the coronavirus from taking hold at all.” – what my free salt water cure does and stops.
    No soreness when you do it, it feels like you are flushing your head with water, if you get sore reaction, you have a virus so deal with it, exactly as I have described above – did a sniffle today – Me, all OK!!
    We all need a cure which works instead of these vaccines, when you get a Flu or Coronavirus infection – now you have one.
    Do not use saline water bought online, use iodine based kitchen or sea salt, it is the iodine in the salt which kills Coronavirus dead
    More to the point, try it on anyone with a Flu or Coronavirus infection and see what happens to the virus and how quickly it is killed in the nasal passages of the head. No Coronavirus, no Covid it would otherwise become. – Simple
    Keep safe – Richard (smile)

  2. We’ll start the tests on hospitalized humans right away (Were these patients aware??) The drug “Seemed” to reduce symptoms, so we’ll end the human study and move forward with production. We’ll test it on animals later.
    Is it just me, or do they “seem” to be doing EVRYTHING backwards ??
    Frankenstein indeed !! At this point, blood letting would be preferred !!!

  3. The Indians have a safe and effective treatment already. They have huge districts in their own country 95% covid-free thanks to ivermectin. You could look it up. You’d think Indian officials would. Maybe Big Pharma is dangling financial incentives? Nah, who would do such a thing?

  4. Who pays the “independent advisory board that … recommended that recruitment into the study be stopped early because of ‘convincing’ evidence of the drug’s benefits, reducing the risk of hospitalization or death by 48%.” The importance is not only who pays, but the inclusion of DEATH in the statement is entirely misleading. You can’t say that it reduces hospitalization OR DEATH because not everyone who is hospitalized dies. This is propaganda; a sales pitch for suckers. Why do they refuse to do animal testing? Why do they not want to test for the results of creating many new mutations? What will be the effect of the new mutations in those who have already had their natural immunity curtailed by the spike vax?

  5. Exactly, and if I’m not mistaken, Merck is the manufacturer of Ivermectin. It must be too cheaply sold to make the big killing off of (pun intended).

  6. I would suggest that the water one should use in this process be that of filtered water and NOT tap water! The scum that comes from our tap water is bad enough to have to bathe in let alone put into one’s body. That’s why we bought a filtering system to remove all of that scum and gunk and whatever else is in that water. If I don’t wipe down the sinks and tub then a slimy, orange material builds and it is absolutely disgusting. Just a suggestion. Thanks for the information. God Bless you and yours.

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  9. Merck owned the patent, which has run out, allowing generic manufacturers to make it cheaply.

  10. Thank you for this. It is so simple, really, it insults the authorities. I have heard of using the Netty pot for cleaning out the nasal passages, gargling Listerine and/or salt water, and nebulizing hydrogen peroxide solution, one/four.

  11. Under emergency use bs they make more money then they would ivermectin.

    All just low life drug pushers .

    “Merck & Co, which develops the anti-parasite drug ivermectin, will soon begin late-stage trials for molnupiravir, which could combat viruses like CovidIvermectin has been incorrectly heralded as a potential COVID-19 treatment due to a misinterpreted study from March 2020

    Parasite experts say that ivermectin has no virus killing properties and is ineffective against COVID-19
    Merck hopes to distribute molnupiravir through out India to help combat the virus while the nation waits for vaccinesThe developer of ivermectin is performing late-stage trials on a drug that could actually prevent COVID-19.
    Merck & Co partnered with Ridgeback Biotherapeutics to develop molnupiravir.

    http:  //www.  mr-mehra  .com/2021/09/developer-of-ivermectin-begins-late.html?m=1

    Anyone who can make you believe absurdities can make you commit atrocities- Voltaire

  12. @J West Be honest, … the information wouldn’t even need a paragraph.

    Steam out your sinuses. there, I fixed it right up. lmao

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