IgG4 Increases With Repeated mRNA Vaccines: Linked To Disease

According to a study titled “IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein,” it has been found that IgG4 levels increase with repeated administration of mRNA vaccines.

A peer-reviewed study entitled “IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein” reports, “recent investigations have found abnormally high levels of IgG4 in people who were administered two or more injections of the mRNA vaccines.” The paper states, “compelling evidence shows that among COVID-19 vaccines, only the mRNA vaccines (but not the adenoviral vector-based vaccine from AstraZeneca) induced a remarkable increase in IgG4 levels.”

The paper was published on May 17, 2023, in a special issue entitled “SARS-CoV-2: Immune Tolerance and Autoimmune Diseases after COVID-19 Vaccination and Its Related Adverse Events” of the  Vaccines Journal featured in the “COVID-19 Vaccines and Vaccination” section of the Journal featuring 1397 papers on all facets of the COVID-19 vaccines and their administration.

Dr. Mikolaj Raszek, Founder and managing director of Merogenomics Inc., provides an excellent summary explanation of the findings below:

Repeated Doses of mRNA Vaccines Increase lgG4 Levels

The paper’s findings are worrisome because it shows evidence that repeated mRNA vaccinations can cause disease due to increased IgG4 levels. According to the paper, “Increased IgG4 synthesis due to repeated mRNA vaccination with high antigen concentrations may also cause autoimmune diseases and promote cancer growth and autoimmune myocarditis in susceptible individuals.”

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lgG4 Immune Evasion/Figure 3/https://www.mdpi.com/2076-393X/11/5/991

Importantly, the paper also notes that “lethal COVID-19 cases have been linked to higher levels of IgG4 antibodies, and it has also been documented that mRNA vaccines trigger their synthesis.” Researchers have thus begun to look at the effect of repeated doses of the mRNA vaccine and their potential for causing illness and disease.

The paper confirms what is becoming increasingly apparent to anyone who has been paying attention—immunity from mRNA vaccines “rapidly wanes.” The paper also confirms that mRNA vaccines do not prevent hospitalization and severe disease in people with comorbidities and that the vaccines “do not produce sterilizing immunity.” As a result, many individuals “suffer frequent re-infections” of the virus. According to the paper, “All three anti-COVID-19 vaccines: Pfizer, Moderna, and Astra Zeneca ChAdOx1, (Cambridge, UK) appeared to be only transiently protective against SARS-CoV-2 infection and transmission.”

The Israel Ministry of Health (MOH) responded to a formal request from an attorney, stating that zero young, healthy individuals have died of COVID-19.

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